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A low intraepithelial effector (CD3+):regulatory (FoxP3+) T-cell ratio predicts adverse outcome of human colon carcinoma
BACKGROUND & AIMS: Regulatory T cells (Tregs) express the forkhead box transcription factor (FoxP3) and suppress the anti-tumor immune response. We investigated whether the intratumoral densities of FoxP3+ and effector CD3+ lymphocytes are associated with prognosis of patients with colon cancer....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873775/ https://ncbi.nlm.nih.gov/pubmed/19577568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.06.053 |
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