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Incision by UvrABC excinuclease is a step in the path to mutagenesis by psoralen crosslinks in Escherichia coli.

4,5',8-Trimethylpsoralen (psoralen) plus near UV light produces interstrand crosslinks and monoadducts in DNA, both of which are mutagenic. In Escherichia coli, crosslinks are incised by UvrABC excinuclease, an event that can lead to homologous recombination and repair. To determine whether UvrABC i...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sladek, F M, Melian, A, Howard-Flanders, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2657732/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.11.3982
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