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Smoking-dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of COPD

When exposed to specific microenvironment, macrophages acquire either M1- or M2-polarized phenotypes associated with inflammation and tissue remodeling, respectively. Alveolar macrophages (AM) directly interact with environmental stimuli such as cigarette smoke, the major risk factor for chronic obs...

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Bibliografische gegevens
Hoofdauteurs: Shaykhiev, Renat, Krause, Anja, Salit, Jacqueline, Strulovici-Barel, Yael, Harvey, Ben-Gary, O’Connor, Timothy P., Crystal, Ronald G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873685/
https://ncbi.nlm.nih.gov/pubmed/19635926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900473
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