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A cell line producing recombinant nerve growth factor evokes growth responses in intrinsic and grafted central cholinergic neurons.

The rat beta nerve growth factor (NGF) gene was inserted into a mammalian expression vector and cotransfected with a plasmid conferring resistance to neomycin into mouse 3T3 fibroblasts. From this transfection a stable cell line was selected that contains several hundred copies of the rat NGF gene a...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ernfors, P, Ebendal, T, Olson, L, Mouton, P, Strömberg, I, Persson, H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287352/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2734317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4756
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