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Phosphatidylinositol 3-kinase inhibitor(LY294002) induces apoptosis of human nasopharyngeal carcinoma in vitro and in vivo

BACKGROUND: To evaluate whether PI3K/Akt pathway could effect on apoptosis and its mechanism in nasopharyngeal carcinoma cells. METHODS: The activation of the PI3K/Akt and its effect on CNE-2Z cells in vivo and in vitro was investigated by MTT assay, flow cytometry, western blot, ELISA, terminal deo...

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Autori principali: Jiang, Hanguo, Fan, Desheng, Zhou, Gengyin, Li, Xiaofang, Deng, Huihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873422/
https://ncbi.nlm.nih.gov/pubmed/20412566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-34
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