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Nucleoside Drugs Induce Cellular Differentiation by Caspase-Dependent Degradation of Stem Cell Factors

BACKGROUND: Stem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells are thus of major importance for cancer therapy. Differentiation therapy by nucleoside drugs represents an attractiv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Musch, Tanja, Öz, Yuva, Lyko, Frank, Breiling, Achim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873290/
https://ncbi.nlm.nih.gov/pubmed/20502711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010726
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