Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype

BACKGROUND: A major feature of chronic obstructive pulmonary disease (COPD) is airway remodelling, which includes an increased airway smooth muscle (ASM) mass. The mechanisms underlying ASM remodelling in COPD are currently unknown. We hypothesized that cigarette smoke (CS) and/or lipopolysaccharide...

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Main Authors: Pera, Tonio, Gosens, Reinoud, Lesterhuis, Andries H, Sami, Riham, Toorn, Marco van der, Zaagsma, Johan, Meurs, Herman
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873257/
https://ncbi.nlm.nih.gov/pubmed/20429916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-48
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