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Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype

BACKGROUND: A major feature of chronic obstructive pulmonary disease (COPD) is airway remodelling, which includes an increased airway smooth muscle (ASM) mass. The mechanisms underlying ASM remodelling in COPD are currently unknown. We hypothesized that cigarette smoke (CS) and/or lipopolysaccharide...

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Autors principals: Pera, Tonio, Gosens, Reinoud, Lesterhuis, Andries H, Sami, Riham, Toorn, Marco van der, Zaagsma, Johan, Meurs, Herman
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873257/
https://ncbi.nlm.nih.gov/pubmed/20429916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-48
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