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Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface

Accurate chromosome segregation requires carefully regulated interactions between kinetochores and microtubules, but how plasticity is achieved to correct diverse attachment defects remains unclear. Here, we demonstrate that Aurora B kinase phosphorylates three spatially distinct targets within the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Welburn, Julie P. I., Vleugel, Mathijs, Liu, Dan, Yates, John R., Lampson, Michael A., Fukagawa, Tatsuo, Cheeseman, Iain M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873218/
https://ncbi.nlm.nih.gov/pubmed/20471944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.034
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