Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

Regulated interactions between kinetochores and spindle microtubules are essential to maintain genomic stability during chromosome segregation. The Aurora B kinase phosphorylates kinetochore substrates to destabilize kinetochore–microtubule interactions and eliminate incorrect attachments. These sub...

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Detalhes bibliográficos
Main Authors: Liu, Dan, Vleugel, Mathijs, Backer, Chelsea B., Hori, Tetsuya, Fukagawa, Tatsuo, Cheeseman, Iain M., Lampson, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845083/
https://ncbi.nlm.nih.gov/pubmed/20231380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001006
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