Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

Regulated interactions between kinetochores and spindle microtubules are essential to maintain genomic stability during chromosome segregation. The Aurora B kinase phosphorylates kinetochore substrates to destabilize kinetochore–microtubule interactions and eliminate incorrect attachments. These sub...

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Hlavní autoři: Liu, Dan, Vleugel, Mathijs, Backer, Chelsea B., Hori, Tetsuya, Fukagawa, Tatsuo, Cheeseman, Iain M., Lampson, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845083/
https://ncbi.nlm.nih.gov/pubmed/20231380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001006
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