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Homology Modeling and Molecular Dynamics Simulations of the Glycine Receptor Ligand Binding Domain

We present a homology based model of the ligand binding domain (LBD) of the homopentameric alpha1 glycine receptor (GlyR). The model is based on multiple sequence alignment with other members of the nicotinicoid ligand gated ion channel superfamily and two homologous acetylcholine binding proteins (...

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Main Authors: Speranskiy, Kirill, Cascio, Michael, Kurnikova, Maria
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873197/
https://ncbi.nlm.nih.gov/pubmed/17357155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21251
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