Genetic variation in PCDH11X is associated with susceptibility to late onset Alzheimer's disease

By analyzing late onset Alzheimer's disease (LOAD) in a genome wide association study (313,504 SNPs, 3 series, 844 cases/1,255 controls) and evaluating the 25 SNPs with most significant allelic association in 4 additional series (1,547 cases/1,209 controls), we identified a SNP (rs5984894) on X...

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Autori principali: Carrasquillo, Minerva M., Zou, Fanggeng, Pankratz, V. Shane, Wilcox, Samantha L., Ma, Li., Walker, Louise P., Younkin, Samuel G., Younkin, Curtis S., Younkin, Linda H., Bisceglio, Gina D., Ertekin-Taner, Nilufer, Crook, Julia E., Dickson, Dennis W., Petersen, Ronald C., Graff-Radford, Neill R., Younkin, Steven G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873177/
https://ncbi.nlm.nih.gov/pubmed/19136949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.305
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