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Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages
Forced expression of the four transcription factors Oct4, Sox2, c-Myc, and Klf4 is sufficient to confer a pluripotent state upon the murine fibroblast genome, generating induced pluripotent stem (iPS) cells. Although felt to be equivalent to embryonic stem (ES) cells, the differentiation potential o...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873147/ https://ncbi.nlm.nih.gov/pubmed/18450826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0033 |
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