Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells.
We have developed a system that permits analysis of targeted homologous recombination at an endogenous, chromosomal gene locus in cultured mammalian cells. Using a hemizygous, adenine phosphoribosyltransferase (APRT)-deficient, Chinese hamster ovary (CHO) cell mutant as a transfection recipient, we...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1989
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2734308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4574 |
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