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QSAR models for predicting cathepsin B inhibition by small molecules—Continuous and binary QSAR models to classify cathepsin B inhibition activities of small molecules

Cathepsin B is a potential target for the development of drugs to treat several important human diseases. A number of inhibitors targeting this protein have been developed in the past several years. Recently, a group of small molecules were identified to have inhibitory activity against cathepsin B...

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Hlavní autoři: Zhou, Zhigang, Wang, Yanli, Bryant, Stephen H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science, Inc 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873115/
https://ncbi.nlm.nih.gov/pubmed/20194042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2010.01.009
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