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Protein Kinase C Inhibits Autophagy and Phosphorylates LC3
During autophagy, the microtubule-associated protein light chain 3 (LC3), a specific autophagic marker in mammalian cells, is processed from the cytosolic form (LC3-I) to the membrane-bound form (LC3-II). In HEK293 cells stably expressing FLAG-tagged LC3, activation of protein kinase C inhibited the...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873090/ https://ncbi.nlm.nih.gov/pubmed/20398630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.04.030 |
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