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Enhanced Sensitivity of Pancreatic Cancer Cells to Concurrent Inhibition of Aberrant Signal Transducer and Activator of Transcription 3 and Epidermal Growth Factor Receptor or Src

Many molecular aberrations occur in pancreatic cancer. Although aberrant epidermal growth factor receptor (EGFR), Src, and signal transducer and activator of transcription 3 (Stat3) are implicated in pancreatic cancer, therapies that target only one of these entities are undermined by signaling cros...

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Autori principali: Jaganathan, Soumya, Yue, Peibin, Turkson, James
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872953/
https://ncbi.nlm.nih.gov/pubmed/20100905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.162669
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