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Profilin-1 overexpression inhibits proliferation of MDA-MB-231 breast cancer cells partly through p27(kip1) upregulation
Profilin-1 (Pfn1), a ubiquitously expressed actin-binding protein, has gained interest in epithelial-derived cancer because of its downregulation in expression in various adenocarcinoma. Pfn1 overexpression impairs tumorigenic ability of human breast cancer xenografts thus suggesting that Pfn1 could...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872929/ https://ncbi.nlm.nih.gov/pubmed/20143334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22058 |
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