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The Role of Transcription Factor Pitx3 in Dopamine Neuron Development and Parkinson's Disease

Parkinson's disease (PD) is characterized by the selective loss of dopamine (DA) neurons in the substantia nigra compacta (SNc). The transcription factor Pitx3 is important for the differentiation and maintenance of midbrain DA neurons during development. There is highly restricted and constitu...

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Detalhes bibliográficos
Main Authors: Li, Jia, Dani, John A., Le, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872921/
https://ncbi.nlm.nih.gov/pubmed/19754401
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