Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair

A recent study suggested that human Cdc14B phosphatase has a central function in the G2 DNA damage checkpoint. In this study, we show that chicken DT40, human HCT116, and human telomerase reverse transcription–immortalized retinal pigment epithelial cells deleted for the Cdc14A or Cdc14B gene are DN...

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Hlavní autoři: Mocciaro, Annamaria, Berdougo, Eli, Zeng, Kang, Black, Elizabeth, Vagnarelli, Paola, Earnshaw, William, Gillespie, David, Jallepalli, Prasad, Schiebel, Elmar
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872905/
https://ncbi.nlm.nih.gov/pubmed/20479464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200910057
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