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Genomic features defining exonic variants that modulate splicing
BACKGROUND: Single point mutations at both synonymous and non-synonymous positions within exons can have severe effects on gene function through disruption of splicing. Predicting these mutations in silico purely from the genomic sequence is difficult due to an incomplete understanding of the multip...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872880/ https://ncbi.nlm.nih.gov/pubmed/20158892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-2-r20 |
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