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Genomic features defining exonic variants that modulate splicing

BACKGROUND: Single point mutations at both synonymous and non-synonymous positions within exons can have severe effects on gene function through disruption of splicing. Predicting these mutations in silico purely from the genomic sequence is difficult due to an incomplete understanding of the multip...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Woolfe, Adam, Mullikin, James C, Elnitski, Laura
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872880/
https://ncbi.nlm.nih.gov/pubmed/20158892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-2-r20
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