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Cardioprotection by kappa-opioid receptor agonist U50488H is mediated by opioidergic regulation but not by calcium current modulation

BACKGROUND: Because the κ-opioid receptor (OR) agonist U50488H stimulates opioidergic regulation and inhibits L-type Ca(2+) channels, this study was aimed at assessing the roles of OR and L-type Ca(2+) channels on U50488H-induced cardioprotection. METHODS: Langendorff-perfused rat hearts were subjec...

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Bibliografski detalji
Glavni autori: Chun, Kook Jin, Jang, Young Ho, Kim, June Hong, Kim, Jun, Park, Yong Hyun
Format: Artigo
Jezik:Inglês
Izdano: The Korean Society of Anesthesiologists 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872865/
https://ncbi.nlm.nih.gov/pubmed/20498795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4097/kjae.2010.58.2.162
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