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Invariant U2 snRNA nucleotides form a stem loop to recognize the intron early in splicing
U2 snRNA-intron branchpoint pairing is a critical step in pre-mRNA recognition by the splicing apparatus, but the mechanism by which these two RNAs engage each other is unknown. Here we identify a new U2 snRNA structure, the branchpoint interaction stem-loop (BSL), that presents the U2 nucleotides t...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872779/ https://ncbi.nlm.nih.gov/pubmed/20471947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.036 |
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