Low-dose dexamethasone prevents endotoxaemia-induced muscle protein loss and impairment of carbohydrate oxidation in rat skeletal muscle

We recently provided evidence suggesting a role for cytokine-mediated inhibition of Akt/Forkhead box O 1 (FOXO1) signalling in the induction of muscle atrophy and impairment of muscle carbohydrate oxidation during lipopolysaccharide (LPS)-induced endotoxaemia in rats. We hypothesized that a low-dose...

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Autores principales: Crossland, Hannah, Constantin-Teodosiu, Dumitru, Greenhaff, Paul L, Gardiner, Sheila M
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2010
Materias:
Skeletal Muscle and Exercise
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872737/
https://ncbi.nlm.nih.gov/pubmed/20176631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.183699
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