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Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers

The cystic fibrosis transmembrane conductance regulator (CFTR) is an integral membrane glycoprotein which functions as an anion channel and influences diverse cellular processes. We studied its role in the development of epithelial tightness by expressing wild-type (WT-CFTR) or mutant (ΔF508-CFTR) C...

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Detalhes bibliográficos
Main Authors: LeSimple, Pierre, Liao, Jie, Robert, Renaud, Gruenert, Dieter C, Hanrahan, John W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872727/
https://ncbi.nlm.nih.gov/pubmed/20156845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.182246
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