Unique physical properties and interactions of the domains of methylated DNA binding protein 2 (MeCP2)

MeCP2 is a methyl CpG binding protein whose key role is the recognition of epigenetic information encoded in DNA methylation patterns. Mutation or mis-regulation of MeCP2 function leads to Rett syndrome as well as a variety of other Autism Spectrum Disorders. Here, we have analyzed in detail the pro...

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Main Authors: Ghosh, Rajarshi P., Nikitina, Tatiana, Horowitz-Scherer, Rachel A., Gierasch, Lila M., Uversky, Vladimir N., Hite, Kristopher, Hansen, Jeffrey C., Woodcock, Christopher L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872689/
https://ncbi.nlm.nih.gov/pubmed/20405910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9019753
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