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A Thermally Targeted Peptide Inhibitor of Symmetrical Dimethylation Inhibits Cancer Cell Proliferation

Targeting splicing machinery components is an underdeveloped strategy for cancer therapy. Uridine-rich small nuclear ribonucleoproteins (UsnRNPs) are essential spliceosome components that recognize splice sites in newly transcribed RNA. The major spliceosomal snRNPs are comprised of UsnRNA bound by...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bidwell, Gene L., Whittom, Angela A., Thomas, Emily, Lyons, Daniel, Hebert, Michael D., Raucher, Drazen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872552/
https://ncbi.nlm.nih.gov/pubmed/20167239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.02.007
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