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A Thermally Targeted Peptide Inhibitor of Symmetrical Dimethylation Inhibits Cancer Cell Proliferation
Targeting splicing machinery components is an underdeveloped strategy for cancer therapy. Uridine-rich small nuclear ribonucleoproteins (UsnRNPs) are essential spliceosome components that recognize splice sites in newly transcribed RNA. The major spliceosomal snRNPs are comprised of UsnRNA bound by...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872552/ https://ncbi.nlm.nih.gov/pubmed/20167239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.02.007 |
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