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In vivo role of leukocyte ADAM17 in the inflammatory and host responses during E. coli-mediated peritonitis

Inflammation is the body’s initial response to infection, which is harmful when excessive, as exemplified in sepsis inflammatory syndromes. Ectodomain shedding by the membrane metalloprotease ADAM17 is an emerging regulator of inflammation, as it directs the activity of various inflammatory modulato...

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Detalhes bibliográficos
Main Authors: Long, Chunmei, Wang, Yue, Herrera, Amy H., Horiuchi, Keisuke, Walcheck, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872538/
https://ncbi.nlm.nih.gov/pubmed/20154226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1109763
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