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TRPC channels are necessary mediators of pathologic cardiac hypertrophy

Pathologic hypertrophy of the heart is regulated through membrane-bound receptors and intracellular signaling pathways that function, in part, by altering Ca(2+) handling and Ca(2+)-dependent signaling effectors. Transient receptor potential canonical (TRPC) channels are important mediators of Ca(2+...

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Bibliographic Details
Main Authors: Wu, Xu, Eder, Petra, Chang, Baojun, Molkentin, Jeffery D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872458/
https://ncbi.nlm.nih.gov/pubmed/20351294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001825107
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