Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse model with diabetes

Recent epidemiological studies suggest that diabetes mellitus is a strong risk factor for Alzheimer disease. However, the underlying mechanisms remain largely unknown. In this study, to investigate the pathophysiological interaction between these diseases, we generated animal models that reflect the...

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Detalhes bibliográficos
Main Authors: Takeda, Shuko, Sato, Naoyuki, Uchio-Yamada, Kozue, Sawada, Kyoko, Kunieda, Takanori, Takeuchi, Daisuke, Kurinami, Hitomi, Shinohara, Mitsuru, Rakugi, Hiromi, Morishita, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872449/
https://ncbi.nlm.nih.gov/pubmed/20231468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000645107
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