Chargement en cours...
Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase β binding affinity
Formation of a complex between the XRCC1 N-terminal domain (NTD) and DNA polymerase β (Pol β) is central to base excision repair of damaged DNA. Two crystal forms of XRCC1-NTD complexed with Pol β have been solved, revealing that the XRCC1-NTD is able to adopt a redox-dependent alternate fold, chara...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872404/ https://ncbi.nlm.nih.gov/pubmed/20351257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914077107 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|