Influence of the Lipid Anchor Motif of N-Ras on the Interaction with Lipid Membranes: A Surface Plasmon Resonance Study

Ras GTPases play a crucial role in signal transduction cascades involved in cell differentiation and proliferation, and membrane binding is essential for their proper function. To determine the influence of the nature of the lipid anchor motif and the difference between the active (GTP) and inactive...

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Bibliographic Details
Main Authors: Gohlke, Andrea, Triola, Gemma, Waldmann, Herbert, Winter, Roland
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Membrane
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872271/
https://ncbi.nlm.nih.gov/pubmed/20483331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.005
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