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Retardation of Aβ Fibril Formation by Phospholipid Vesicles Depends on Membrane Phase Behavior

An increasing amount of evidence suggests that in several amyloid diseases, the fibril formation in vivo and the mechanism of toxicity both involve membrane interactions. We have studied Alzheimer's disease related amyloid beta peptide (Aβ). Recombinant Aβ(M1–40) and Aβ(M1–42) produced in Esche...

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Bibliographic Details
Main Authors: Hellstrand, Erik, Sparr, Emma, Linse, Sara
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872260/
https://ncbi.nlm.nih.gov/pubmed/20483329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.063
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