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Retardation of Aβ Fibril Formation by Phospholipid Vesicles Depends on Membrane Phase Behavior
An increasing amount of evidence suggests that in several amyloid diseases, the fibril formation in vivo and the mechanism of toxicity both involve membrane interactions. We have studied Alzheimer's disease related amyloid beta peptide (Aβ). Recombinant Aβ(M1–40) and Aβ(M1–42) produced in Esche...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872260/ https://ncbi.nlm.nih.gov/pubmed/20483329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.063 |
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