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Retardation of Aβ Fibril Formation by Phospholipid Vesicles Depends on Membrane Phase Behavior

An increasing amount of evidence suggests that in several amyloid diseases, the fibril formation in vivo and the mechanism of toxicity both involve membrane interactions. We have studied Alzheimer's disease related amyloid beta peptide (Aβ). Recombinant Aβ(M1–40) and Aβ(M1–42) produced in Esche...

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Autors principals: Hellstrand, Erik, Sparr, Emma, Linse, Sara
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872260/
https://ncbi.nlm.nih.gov/pubmed/20483329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.063
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