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Circular Dichroism Reveals Evidence of Coupling Between Immunoglobulin Constant and Variable Region Secondary Structure
Antibodies (Ab) are bifunctional molecules with two domains, a constant region (C) that confers effector properties and a variable (V) region responsible of antigen (Ag) binding. Historically the C and V regions were considered to be functionally independent, with Ag specificity being solely determi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872143/ https://ncbi.nlm.nih.gov/pubmed/20299100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.02.018 |
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