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THE CLOCK GENES PERIOD 1 AND PERIOD 2 MEDIATE DIURNAL RHYTHMS IN DIOXIN-INDUCED CYP1A1 EXPRESSION IN THE MOUSE MAMMARY GLAND AND LIVER

Transcription factors expressing Per-Arnt-Sim (PAS) domains are key components of the mammalian circadian clockworks found in most cells and tissues. Because these transcription factors interact with other PAS genes mediating xenobiotic metabolism and because toxin responses are often marked by dail...

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Detalhes bibliográficos
Main Authors: Qu, Xiaoyu, Metz, Richard P., Porter, Weston W., Neuendorff, Nichole, Earnest, Barbara J., Earnest, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872133/
https://ncbi.nlm.nih.gov/pubmed/20371273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2010.03.020
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