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Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver
The aryl hydrocarbon receptor (AhR) and AhR nuclear translocator (ARNT) are transcription factors that express Per-Arnt-Sim (PAS) DNA-binding motifs and mediate the metabolism of drugs and environmental toxins in the liver. Because these transcription factors interact with other PAS genes in molecul...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711551/ https://ncbi.nlm.nih.gov/pubmed/19038280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.10.016 |
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