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Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver

The aryl hydrocarbon receptor (AhR) and AhR nuclear translocator (ARNT) are transcription factors that express Per-Arnt-Sim (PAS) DNA-binding motifs and mediate the metabolism of drugs and environmental toxins in the liver. Because these transcription factors interact with other PAS genes in molecul...

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Détails bibliographiques
Auteurs principaux: Qu, Xiaoyu, Metz, Richard P., Porter, Weston W., Cassone, Vincent M., Earnest, David J.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711551/
https://ncbi.nlm.nih.gov/pubmed/19038280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.10.016
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