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Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia

Both increased Estrogen Receptor (ER)α expression and germline disruption of one p53 allele increase breast cancer risk in women. Genetically engineered mouse models of deregulated ERα expression and p53 haploinsufficiency were used to investigate similarities and differences of each genetic lesion...

詳細記述

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書誌詳細
主要な著者: Díaz-Cruz, Edgar S., Furth, Priscilla A.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872114/
https://ncbi.nlm.nih.gov/pubmed/20466998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3450
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