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UDP-(5F)-GlcNAc acts as a slow-binding inhibitor of MshA, a retaining glycosyltransferase

[Image: see text] Glycosyltransferase enzymes play important roles in numerous cellular pathways. Despite their participation in many therapeutically-relevant pathways, there is a paucity of information on how to effectively inhibit this class of enzymes. Here we report that UDP-(5F)-GlcNAc acts as...

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Autors principals: Frantom, Patrick A., Coward, James K., Blanchard, John S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872082/
https://ncbi.nlm.nih.gov/pubmed/20411981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101231a
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