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Biomolecular Surface Engineering of Pancreatic Islets with Thrombomodulin
Islet transplantation has emerged as a promising treatment for Type 1 diabetes, but its clinical impact remains limited by early islet destruction mediated by prothrombotic and innate inflammatory responses elicited upon transplantation. Thrombomodulin (TM) acts as an important regulator of thrombos...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872068/ https://ncbi.nlm.nih.gov/pubmed/20102751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2010.01.027 |
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