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Biomolecular Surface Engineering of Pancreatic Islets with Thrombomodulin

Islet transplantation has emerged as a promising treatment for Type 1 diabetes, but its clinical impact remains limited by early islet destruction mediated by prothrombotic and innate inflammatory responses elicited upon transplantation. Thrombomodulin (TM) acts as an important regulator of thrombos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wilson, John T., Haller, Carolyn A., Qu, Zheng, Cui, Wanxing, Urlam, Murali K., Chaikof, Elliot L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872068/
https://ncbi.nlm.nih.gov/pubmed/20102751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2010.01.027
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