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Epstein-Barr Virus BRLF1 Inhibits Transcription of IRF3 and IRF7 and Suppresses Induction of Interferon-β

Activation of interferon regulatory factors (IRFs) 3 and 7 is essential for the induction of Type I interferons (IFN) and innate antiviral responses, and herpesviruses have evolved mechanisms to evade such responses. We previously reported that Epstein-Barr Virus BZLF1, an immediate-early (IE) prote...

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Autors principals: Bentz, Gretchen L., Liu, Renshui, Hahn, Angela M., Shackelford, Julia, Pagano, Joseph S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871977/
https://ncbi.nlm.nih.gov/pubmed/20381110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.014
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