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S-phase induction and transformation of quiescent NIH 3T3 cells by microinjection of phospholipase C.
Two inositol phospholipid-specific phospholipase C (PLC) isozymes (PLC-I and -II) have been purified from bovine brain. When PLC-I or PLC-II was microinjected (100-700 micrograms/ml) into quiescent NIH 3T3 cells, a time- and dose-dependent induction of DNA synthesis occurred, as demonstrated by [3H]...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1989
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3659 |
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