S-phase induction and transformation of quiescent NIH 3T3 cells by microinjection of phospholipase C.

Two inositol phospholipid-specific phospholipase C (PLC) isozymes (PLC-I and -II) have been purified from bovine brain. When PLC-I or PLC-II was microinjected (100-700 micrograms/ml) into quiescent NIH 3T3 cells, a time- and dose-dependent induction of DNA synthesis occurred, as demonstrated by [3H]...

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Библиографические подробности
Главные авторы: Smith, M R, Ryu, S H, Suh, P G, Rhee, S G, Kung, H F
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC287197/
https://ncbi.nlm.nih.gov/pubmed/2726744
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