A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II.

The unique C-terminal repeat domain (CTD) of the largest subunit (IIa) of eukaryotic RNA polymerase II consists of multiple repeats of the heptapeptide consensus sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. The number of repeats ranges from 26 in yeast to 42 in Drosophila to 52 in mouse. The CTD is essenti...

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Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Lee, J M, Greenleaf, A L
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1989
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2657724/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3624
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