Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: implications for heparin efficacy.

Fibrin II monomer has a dramatic inhibitory effect on the rate of heparin-catalyzed inactivation of human alpha-thrombin by antithrombin III. At 6 microM fibrin II monomer, equivalent to the concentration of fibrinogen in plasma, the second-order rate constant was reduced by a factor of 308--from 2....

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Опубліковано в::	Proc Natl Acad Sci U S A
Автори:	Hogg, P J, Jackson, C M
Формат:	Artigo
Мова:	Inglês
Опубліковано:	National Academy of Sciences 1989
Предмети:	Research Article
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726739/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3619
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