Influence of abasic and anucleosidic sites on the stability, conformation, and melting behavior of a DNA duplex: correlations of thermodynamic and structural data.

We report a complete thermodynamic characterization of the impact of abasic and anucleosidic lesions on the stability, conformation, and melting behavior of a DNA duplex. The requisite thermodynamic data were obtained by using a combination of spectroscopic and calorimetric techniques to investigate...

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Detalles Bibliográficos
Main Authors: Vesnaver, G, Chang, C N, Eisenberg, M, Grollman, A P, Breslauer, K J
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC287188/
https://ncbi.nlm.nih.gov/pubmed/2726738
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