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Influence of abasic and anucleosidic sites on the stability, conformation, and melting behavior of a DNA duplex: correlations of thermodynamic and structural data.

We report a complete thermodynamic characterization of the impact of abasic and anucleosidic lesions on the stability, conformation, and melting behavior of a DNA duplex. The requisite thermodynamic data were obtained by using a combination of spectroscopic and calorimetric techniques to investigate...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Vesnaver, G, Chang, C N, Eisenberg, M, Grollman, A P, Breslauer, K J
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1989
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287188/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3614
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