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Experimental genomics of fitness in yeast

The set of single-gene deletions in yeast can be used to evaluate the effect of mutation on fitness over the whole genome. The measurement of growth in pure culture or relative growth in mixtures has confirmed that most deletions have little effect in laboratory culture. Moreover, there is a sharp d...

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Detalhes bibliográficos
Autor principal: Bell, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871833/
https://ncbi.nlm.nih.gov/pubmed/20129976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2009.2099
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