Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

Global quantitative analysis of genetic interactions is a powerful approach for deciphering the roles of genes and mapping functional relationships among pathways. Using colony size as a proxy for fitness, we developed a method for measuring fitness-based genetic interactions from high-density array...

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Detalhes bibliográficos
Main Authors: Baryshnikova, Anastasia, Costanzo, Michael, Kim, Yungil, Ding, Huiming, Koh, Judice, Toufighi, Kiana, Youn, Ji-Young, Ou, Jiongwen, Luis, Bryan-Joseph San, Bandyopadhyay, Sunayan, Hibbs, Matthew, Hess, David, Gingras, Anne-Claude, Bader, Gary D, Troyanskaya, Olga G, Brown, Grant W, Andrews, Brenda, Boone, Charles, Myers, Chad L
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117325/
https://ncbi.nlm.nih.gov/pubmed/21076421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1534
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